其他信息
| 抗体种属性 | Non-human primates, Human |
|---|---|
| 克隆号 | 29E.2A3 |
| 同型对照 | Mouse IgG2b kappa |
| 应用 | IHC(F), FC (QC tested), FUNC |
| 浓度 | 1 mg/ml |
| 保存缓冲液 | Phosphate buffered saline (PBS), pH 7.4 |
| 保存温度 | Store at 2-8°C. Do not freeze. |
| 产品详情链接 |
12-177-C100 | Anti-Hu CD274 Purified Low Endotoxin, 0.1 mg
¥2711.87
CD274 / PD-L1 (programmed death ligand-1), also known as B7-H1, is a member of the B7 family of regulatory proteins. It can act as both costimulatory and coinhibitory molecule for T cells. Interaction with its ligand CD279 (PD1) appears to be important in the maintenance of peripheral tolerance and in prevention of tumor rejection. Even pathogens (e.g. Schistosoma) may exploit CD274 to evade an immune response. Besides CD279, existence of other receptor(s) for CD274 is likely.
