其他信息
| 抗体种属性 | Human, Non-human primates |
|---|---|
| 克隆号 | MEM-18 |
| 同型对照 | Mouse IgG1 |
| 应用 | FC (QC tested), IP, WB, ELISA, FUNC |
| 浓度 | 1 mg/ml |
| 保存缓冲液 | Phosphate buffered saline (PBS), pH 7.4 |
| 保存温度 | Store at 2-8°C. Do not freeze. |
| 产品详情链接 |
12-212-C100 | Anti-Hu CD14 Purified Low Endotoxin, 0.1 mg
¥2711.87
CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where it serves as a multifunctional lipopolysaccharide receptor. It is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.
