1X-433-C100 | Anti-c-Myc tag HRP, 0.1 mg

¥4340.99

The c-myc gene (8q24 on human chromosome) is the cellular homologue of the v-myc gene originally isolated from an avian myelocytomatosis virus. The c-Myc protein is a transcription factor (nuclear localization). c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin-dependent kinase, ERK2 and C-Jun N-terminal Kinase (JNK) in cell proliferation and cell cycle regulation. In normal cells the expression of c-Myc is tightly regulated but in human cancers c-Myc is frequently deregulated. c-Myc is also essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells.

SKU: exbio-1X-433-C100 分类: ,

其他信息

抗体种属性

Tagged fusion proteins in all species, Human

克隆号

9E10

同型对照

Mouse IgG1

应用

WB

浓度

1 mg/ml

保存缓冲液

Stabilizing phosphate buffered saline (PBS), pH 7.4, 0.01% thimerosal

保存温度

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

产品详情链接

https://exbio.cz/research-product/antibodies/tags-and-labels/anti-c-myc-tag-hrp