A4-680-T100 | Anti-EGFR Alexa Fluor® 488, 100 tests

¥3988.14

The oncoprotein EGFR (epidermal growth factor receptor), also known as HER1 / ErbB1, is a member of ErbB family of cell surface receptor tyrosine kinases. This 170 kDa transmembrane glycoprotein is often associated with cancerogenesis, although its activation state is controlled at various levels including trafficking and degradation steps. Binding of receptor-specific ligands to the EGFR ectodomain results in formation of homodimeric or heterodimeric kinase-active complexes into which HER2 / ErbB2 is recruited as a preferred partner. Subsequent signaling cascades such as RAS/MAPK and PI3K/AKT pathways lead to cell proliferation and survival responses.

SKU: exbio-A4-680-T100 分类: ,

其他信息

抗体种属性

Horse, Human

Negative species

Mouse, Rat

克隆号

EGFR1

同型对照

Mouse IgG2b kappa

应用

ICC, FC (QC tested), IHC(F)

浓度
保存缓冲液

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

保存温度

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

产品详情链接

https://exbio.cz/research-product/antibodies/cd-and-related-antigens/anti-egfr-alexa-fluor-488