PB-308-T100 | Anti-Hu CD27 Pacific Blue™, 100 tests

¥3988.14

CD27 is a transmembrane 55 kDa protein of the nerve growth factor-receptor family, expressed as a disulfide-linked homodimer on mature thymocytes, peripheral blood T cells and a subpopulation of B cells. Activation of T cells via TCR-CD3 complex results in upregulation of CD27 expression on the plasma membrane as well as in the release of its soluble 28-32 kDa form, sCD27, detected in the plasma, urine or spinal fluid. This sCD27 is an important prognostic marker of acute and chronic B cell malignancies. RgpA, a cystein proteinase, although activating T cells through the protease-activated receptors (PARs), degradates CD27 and counteracts T cell activation mediated by CD27 and its ligand CD70.

SKU: exbio-PB-308-T100 分类: ,

其他信息

抗体种属性

Human

克隆号

LT27

同型对照

Mouse IgG2a

应用

FC (QC tested)

浓度
保存缓冲液

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

保存温度

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

产品详情链接

https://exbio.cz/research-product/antibodies/cd-and-related-antigens/anti-hu-cd27-pacific-blue