PB-579-C100 | Anti-Ms CD8a Pacific Blue™, 0.1 mg

¥3627.78

The CD8a (CD8 alpha) subunit of CD8 T cell coreceptor is expressed in CD8 alpha/beta heterodimers on majority of MHC I-restricted conventional T cells and thymocytes and in CD8 alpha/alpha homodimers on subsets of memory T cells, intraepithelial lymphocytes, NK cells, macrophages and dendritic cells. Regulation of CD8 beta level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 alpha/beta but not alpha/alpha dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8, thereby affecting the functional diversity of the TCR signaling.

SKU: exbio-PB-579-C100 分类: ,

其他信息

抗体种属性

Mouse

克隆号

53-6.7

同型对照

Rat IgG2a kappa

应用

FC (QC tested)

浓度

0.5 mg/ml

保存缓冲液

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

保存温度

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

产品详情链接

https://exbio.cz/research-product/antibodies/cd-and-related-antigens/anti-ms-cd8a-pacific-blue