其他信息
| 抗体种属性 | Human |
|---|---|
| 克隆号 | MEM-170 |
| 同型对照 | Mouse IgG1 |
| 应用 | FC (QC tested), FUNC |
| 浓度 | 1 mg/ml |
| 保存缓冲液 | Phosphate buffered saline (PBS), pH 7.4 |
| 保存温度 | Store at 2-8°C. Do not freeze. |
| 产品详情链接 |
10-502-C100 | Anti-Hu CD11b Purified Azide Free, 0.1 mg
¥2711.87
CD11b (integrin alphaM subunit) is a 165-170 kDa type I transmembrane glycoprotein that non-covalently associates with integrin beta2 subunit (CD18); expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18 integrin (Mac-1, CR3) is highly expressed on NK cells, neutrophils, monocytes and less on macrophages. CD11b/CD18 integrin is implicated in various adhesive interactions of monocytes, macrophages and granulocytes, facilitating their diapedesis, as well as it mediates the uptake of complement coated particles, serving as a receptor for the iC3b fragment of the third complement component.
