其他信息
| 抗体种属性 | Human |
|---|---|
| 克隆号 | 1D11 |
| 同型对照 | Mouse IgG1 kappa |
| 应用 | FC (QC tested), IP, IHC(F), FUNC |
| 浓度 | 1 mg/ml |
| 保存缓冲液 | Phosphate buffered saline (PBS), pH 7.4 |
| 保存温度 | Store at 2-8°C. Do not freeze. |
| 产品详情链接 |
10-650-C100 | Anti-Hu CD314 Purified Azide Free, 0.1 mg
¥2711.87
CD314, also known as NKG2D (natural killer receptor G2D) or KLRK1 (killer cell lectin-like receptor subfamily K, member 1), is a homodimeric C-type lectin-like activating receptor and costimulator with type II membrane orientation (C teminus extracellular). CD314 homodimers are associated with DAP10, a membrane adaptor protein that signals similar to CD28 by recruitment of phosphatidylinositol 3-kinase. Engagement of CD314 amplifies antigen-specific T cell responses in CD314-positive T cell populations. In NK cells, CD314 is a primary activating receptor. As CD314 ligands the MHC class-I chain-related proteins A and B (MICA, MICB) and UL16-binding proteins (ULBPs) have been identified.
