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Histone deacetylase 6 (HDAC6), like other histone deacetylases, affects gene expression by regulation of chromatin remodeling. HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other. Besides histones, HDAC6 deacetylates also other substrates including alpha tubulin and HSP90 alpha, and is involved in protein trafficking and degradation, as well as in affecting of cell shape and migration. Deregulation of HDAC6 expression and activity is associated with many diseases.
| 抗体种属性 | Human |
|---|---|
| 克隆号 | 159 |
| 同型对照 | Mouse IgG1 kappa |
| 应用 | WB, ICC, ELISA, FC (QC tested) |
| 浓度 | 1 mg/ml |
| 保存缓冲液 | Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide |
| 保存温度 | Store at 2-8°C. Do not freeze. |
| 产品详情链接 | https://exbio.cz/research-product/antibodies/nucleus/anti-hdac6-purified-4 |
